Ayano Sekine

Ayano is a supporting character and Shana's best friend. She secretly has feelings for her, but she supports her when she has a crush on Rukasu.

Shana Yogorenaki
Shana is Ayano’s best friend. She has a crush on her, and the feelings stay even after she learns of what she has done. Ayano is the one who knitted the gloves that seal Shana’s powers throughout the third season.

Eimi Ichigomiya
Ayano considers Eimi to be a close friend and expresses worry for her antisocial behavior. She also supports her relationship with Renji.

Hiroshi Tsumetai
Ayano once dated Hiroshi in junior high to secretly prove to herself that she is capable of liking men, but she broke up with him after realizing that she is in love with Shana. Hiroshi worries for a while that she broke up with him because he accidentally rubbed some of his “hate energy” on her, but once the misunderstanding is cleared up, they remain friends.

Rukasu Yamada
Ayano is secretly jealous of Rukasu because of Shana’s crush on him, but otherwise, they’re on good terms.

Trivia

 * To clear some possible confusion on her sexual orientation, Ayano is, indeed, a lesbian.
 * The decision to make Ayano a lesbian came from the creator wanting to include a LGBTQ+ character in the series because of the rainbow flag, and Ayano seemed to her like the "perfect target for liking the same gender".
 * She was going to be bisexual, but the creator decided to change it because why not?